Read e-book online A History of Immunology PDF

By Arthur M. Silverstein

ISBN-10: 012643770X

ISBN-13: 9780126437706

It is a professional-level highbrow heritage of the advance of immunology from approximately 1720 to approximately 1970. starting with the paintings and insights of the early immunologists within the 18th century, Silverstein strains the advance of the most important principles that have shaped immunology right down to the maturation of the self-discipline within the decade following the second one international warfare. Emphasis is put on the philosophic and sociologic weather of the clinical milieu within which immunology has constructed, supplying a historical past to the vast tradition of the self-discipline.

Key Features
* A professional-level highbrow heritage of the advance of immunology from approximately 1720 to 1970, with emphasis put on the social weather of the medical milieu within which sleek immunology evolved
* Written through an writer rather well recognized either as a historian of clinical technological know-how and for his vast study contributions to the immunopathology of the eye
* the one whole heritage of immunology on hand

Show description

Read or Download A History of Immunology PDF

Best immunology books

Janeway's Immunobiology - download pdf or read online

Janeway’s Immunobiology is a textbook that introduces the immune procedure in all its features to undergraduates, and likewise presents a remedy of the topic that's finished adequate to be necessary to graduate scholars drawn to study, and to scientific scholars interested by medical functions. The 8th variation has been completely revised and up-to-date and comes in either print and booklet formats.

Janeway’s Immunobiology maintains to set the traditional for foreign money and authority with its transparent writing kind and association, uniform artwork software, and clinical accuracy. It offers a constant perspective throughout—that of the host’s interplay with an atmosphere containing many species of doubtless damaging microorganisms. The full-color artwork application is conceptually coherent and illustrates the techniques and mechanisms underlying the strategies within the textual content. The sixteen chapters during this readable, available textbook are prepared and offered in this sort of means as to assist carry an entire one-semester immunology path, starting with innate immunity, then relocating to adaptive immunity, and finishing with utilized scientific immunology.

Discussion questions are supplied on the finish of Chapters 2 to sixteen. those questions can be utilized for overview, or because the foundation for dialogue in school or in casual research teams. Summaries finish every one part and every bankruptcy. As in past versions, a caduceus icon within the margins shows themes that are correlated to Case experiences in Immunology, 6th version through Geha and Notarangelo.

New within the 8th variation
<UL> * Innate immunity has been up-to-date and extended and is now awarded in separate chapters (Chapters 2 and 3), in addition to being extra emphasised within the remainder of the textbook.   bankruptcy 2 covers antimicrobial peptides and the supplement approach, and bankruptcy three offers with mobile innate receptors and cell-mediated innate immunity (e. g. TLRs, phagocytosis, NK cells, interferon creation, innate-like lymphocytes).
* The part on supplement has been transformed and reconceived—explaining the lectin pathway first—making it more uncomplicated to coach through putting it into the context of innate recognition.
* Evolution is now integrated during the textual content, aiding scholars see related innovations utilized by diverse organisms.
* The textual content and figures of bankruptcy 7 Signaling via Immune process Receptors were revised to provide a cohesive synthesis of signaling for immunology, targeting more advantageous representation of antigen popularity signaling and lymphocyte activation. Signaling via different receptors is handled anywhere acceptable in the course of the book.
* up to date bankruptcy on B-cell immune responses (Chapter 10), in particular on trafficking of B cells in peripheral lymphoid organs (e. g. lymph nodes) and the destinations at which they come across antigen.
* assurance of mucosal immunity (Chapter 12) has been pointed out thus far, together with responses to the commensal microbiota and the function of specialised dendritic cells and the regulatory T cells in protecting tolerance to foodstuff antigens and commensal bacteria.
* bankruptcy thirteen, disasters of Host protection Mechanisms, has been reorganized and revised to constitution an knowing of basic immunodeficiencies within the context of developmental pathways.
* bankruptcy sixteen, Manipulation of the Immune reaction, has been seriously revised to incorporate a better emphasis on scientific matters and an entire replace of immunotherapeutics and vaccines.
* Many new and revised figures illustrate the tactics and mechanisms underlying the thoughts provided within the textual content.
* The icons used were up to date and extended to include a brand new emphasis on signaling pathways.
* New references were further through the text.

Read e-book online Ciba Foundation Symposium 147 - IgE, Mast Cells and the PDF

Stories contemporary easy learn into IgE, mast cells, and the allergic reaction and the relevance of this paintings to human pathophysiology, and discusses new tools of remedy. This symposium is exclusive within the IgE box for its breadth of insurance and interdisciplinary nature, and it indicates the advantages from the present quick growth of data in mobile biology, immunology, and molecular genetics, in addition to the capability medical value of this learn to scientific immunologists and allergologists.

Get Cancer Immunology: Cancer Immunotherapy for Organ-Specific PDF

Melanoma Immunology is meant as an updated, clinically proper evaluation of melanoma immunology and immunotherapy. This quantity makes a speciality of the immunopathology and immunotherapy of organ cancers intimately. It sincerely explains their immunology and describes novel immunotherapy for particular cancers, together with pediatric strong tumors, hematologic malignancies, gastrointestinal tumors, epidermis cancers, bone and connective tissue tumors, vital apprehensive procedure tumors, lung cancers, genitourinary tract tumors and breast cancers.

Additional info for A History of Immunology

Sample text

Prakt. Chem. May (1879); cited in Sirotinin, Z. Hyg. 4, 262 (1888). 48. A. Chauveau, C. R. Hebd. Seances Acad. Sei. 89,498 (1880); 90, 1526 (1880); 91, 148 (1880). 49. See Chapter 5 and H. Zinsser, Infection and Resistance. Macmillan, New York, 1914. 50. P. M. H. Mazumdar, Bull. Hist. Med. 48, 1 (1974). See also P. M. H. Mazumdar, Karl Landsteiner and the Problem of Species, 1838-1968. Thesis, Johns Hopkins University, Baltimore, Maryland, 1976. 51. E. von Behring, Centralbl. Klin. Med. 9, 681 (1888).

13. L. Pasteur, C. R. Hebd. Seances Acad. Sei. 90, 239, 952 (1880). 14. W. R. Le Fanu, personal communication, 1977. 15. J. Hunter, A Treatise on the Blood, Inflammation, and Gun-shot Wounds. Webster, Philadelphia, Pennsylvania, 1823. 16. J. Baron, Life of Edward Jenner. Colburn, London, 1838. See also W. R. Le Fanu, Edward Jenner. Harvey & Blythe, London, 1951. 17. H. E. Sigerist, A History of Medicine, Vol. I, Chap. 2. Oxford University Press, New York, 1951. See also J. Procope, Medicine, Magic, and Mythology.

J. 1, 1257 (1896). 40. T h e rapid spread of acceptance of vaccination throughout the world, and the resulting adulation of Jenner, can best be compared with the similar response to Pasteur's antirabies treatment of the 1880s. In both instances, the initial evidence on safety and efficacy was incomplete, but the world responded with alacrity and enthusiasm, and even their governments rewarded them. When J e n n e r interceded with the French on behalf of an English prisoner, Napoleon, then at war with England, remarked that he could not refuse anything to this great benefactor of mankind.

Download PDF sample

A History of Immunology by Arthur M. Silverstein

by John

Rated 4.53 of 5 – based on 28 votes